If it touches an enemy it breaks and leave a pool on the floor which freezes enemies and deals 8 damage per tick, * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, * shop room pool, shop item pool, the lost item pool, white, Causes Isaac's head to detach and orbit his body, blocking shots and dealing 7 contact damage per tick, BFFs will cause the Guillotine head to do double damage (14 damage per tick), Tears are still fired from Isaac's head but the hitbox remains around his body, UNLOCK: Unlock this item by beating the Isaac boss with Judas, * item room, treasure room, item room pool, chop, head, silver, metal, Gives Isaac an orbital ball of bandages that deals 7 contact damage per tick and blocks enemy shots, Collecting a second Ball of Bandages in the run turns the orbital into a pink head that shoots tears that deal 7 damage each and have a chance to charm enemies, Getting a third Ball of Bandages will transform the head into bandage girl which will chase enemies dealing 3.5 contact damage per tick while firing charm tears, A fourth Ball of Bandages will make the Bandage Girl bigger and stronger, making her deal 5.5 damage per tick instead, Any further Ball of Bandages will repeat the cycle, Increases the chance of champion enemies appearing by 15%, Doesn't affect the chance for champion bosses to spawn, * shop room pool, shop item pool, red, croissant, crescent, Bombs now become poop bombs, which deal 10 damage to all enemies in the room and daze them for a short period of time, Butt Bombs heal the poop bosses (Dingle, Dangle, Brownie) by 25% of their max HP, * boss rush pool, boss rush room, item room, treasure room, item room pool, poop, face, brown, If Isaac stands still and stops shooting for a second, he turns to stone, making him invincible until he moves/shoots again, Using bombs or your active item will remove the invicibility as well, This item is a reference to the Tanuki suit in Super Mario 3, * item room, treasure room, item room pool, raccoon, green, Spawns 2-5 friendly attack spiders every time you take damage, REPENTANCE - Buffed, used to spawn 1-2 spiders, * item room, treasure room, item room pool, the lost item pool, purple, blue, heart, cute spider baby, When Isaac dies, he has a 50% chance to resurrect with 1/2 a heart, * curse room pool, red chest pool, red chest item pool, devil pool, devil room pool, devil deal, You still take damage however when using Blood Donation machines and Devil Beggars, *, spikes, spikey, spike rock, greyhost, grey host, Causes all pedestal items to show up as rotating items, that swap every 1 second between the original spawned item and a HP up item. card will teleport you to the I AM ERROR room, UNLOCK: Unlock this item by beating the Isaac boss with Eden, * secret room pool, shop room pool, shop item pool, item room, treasure room, item room pool, After killing a 25 more enemies, it transforms again dealing 15 damage and destroying obstacles it charges into. The main purpose of the Cracked Key is to unlock Tainted character in the Home floor without needing to find the Red Key. and Stars? Definitely an honorable mention for sure. You can't use the Red Key to leave this room, The Red Key can be used to open the secret room in the Home floor, which is the method for unlocking alternative 'Tainted' characters, UNLOCK: Unlock this item by opening Mom's Box in the Home floor, Item Pool: Secret Room, Red Chest, Curse Room, Key Beggar, Mom's Chest. If any enemies walk into its path, it will deal 7 contact damage every 7 frames, Nearby enemies will be forced to target and attack it, If the obstacle it is attached to is destroyed then it will continue rolling in the direction it was previously travelling until it meets another wall or obstacle, Causes your bombs to explode into 2-4 tiny bombs, The smaller bombs deal half damage and have a smaller explosion area. No coding knowledge needed! The laser hits up to 13 times if an enemy stays inside it for the duration, Has a chance to drop from the Envy and Super Envy miniboss fights, Item Pool: Item Room, Envy Miniboss, Super Envy Miniboss, * item room, treasure room, item room pool, red, lips, white, eyes, UNLOCK: Unlock this item by beating the Basement 40 times and defeating the Steven boss, *, black, white, face, eyes, mouth, golden chest pool, +10% chance of a devil/angel room opening while held, A second Pentagram will give an extra +5% chance, Counts as 1 of 3 evil items needed towards the Leviathan transformation, Item Pool: Boss Room, Curse Room, Devil Room, Demon Beggar, Crane Game, * curse room pool, devil pool, devil room pool, devil deal, boss room pool, boss room item, ), I would also add the inverted cards, The Stars? white, red, moms eye, mom eye, When used, drops a pool of 'lemonade' on the floor which damages any enemies that come into contact with it for 8 damage per tick, * item room, treasure room, item room pool, yellow, chet lemon, Gives Isaac an orbiting fly which deals 5 contact damage to enemies per tick, * key master pool, key beggar pool, key judgement pool, item room, treasure room, item room pool, communion, the lost item pool, circle, cross, white, yellow, +0.04 Damage Up for every coin you currently have, At 99 coins this item gives +3.96 Damage Up, +0.04 per coin is the amount added before the damage formula is calculated, as this is the only way to show a consistent amount of damage given. +4 damage from Curved Horn instead of 2, -4 Tear Delay from Cancer instead of 2), Item Pool: Shop, Greed Mode Shop, Mom's Chest, Randomly while firing tears, Isaac will stop firing and turn red, where he will charge and release a lot of 'tears' in one go. 14 Psy Fly. I'm sure this will help a lot of new players. ?, Satan and The Lamb as Tainted Cain, Spawns a sack at the start of each new floor, UNLOCK: Unlock this trinket by defeating Mother as Tainted Cain, Causes an Item Room and Shop to appear in Sheol, UNLOCK: Unlock this trinket by defeating Isaac, ?? Doesn't include Curse Room doors or spiked rocks, Tears can be controlled mid-flight using the directional keys, In addition to regular tears, Isaac will sometimes fire extra spectral tears that orbit around him, Fully heals all your red heart containers, Isaac now emits a large light aura that damages nearby enemies 5 times per second while touching it, The visual effect is similar to the effect given to tears by the GodHead item, The aura deals more damage towards the center, ranging from 0.75 at max range to 4 damage when touching Isaac, In addition to normal tears, Isaac now also fires a set of 4 quadshot tears with a slowing effect, The quadshot tears deal 1.5 damage each and do not scale with your damage upgrades, Upon taking damage, you have a chance to dislodge the spider from your face. However, some are a little more hidden, including what might be Repentance's most interesting series of unlocks. The actual explosion deals flat 60 damage, Pestilence (Green) - Poisons the enemy it attacks, Famine (Brown) - Applies a slowing effect, Death (Black) - Deals x4 damage instead of x2, UNLOCK: Unlock this trinket by defeating Isaac, ?? Function: Every item pedestal cycles through 5 different options really fast, Unlock Condition: Defeat the Beast as Tainted Isaac. The new rooms contain 0-3 Devil Deal Items, 1-3 Black Hearts and random enemies from the Sheol floor, UNLOCK: Unlock this trinket by defeating Mother as Tainted Judas, Opens the door to the Blue Womb, regardless of whether you meet the 30 minute speed timer, Opening Pandora's Box while holding this item will ignore the normal effect and instead spawn 6 item pedestals from random item pools. The Planetarium is a type of room that is featured in The. THEGHOST. Supper = +0.5 tears, +1 luck. UNLOCK: Unlock this item by defeating Delirium in The Void floor with Isaac, A one time use active item that when used, will spawn 2 random item pedestals from the item pool associated with the current room (e.g. Having a golden version of this trinket counts as 2 keys. With Keeper's buff of an additional Coin Heart, unlocking this item isn't that difficult compared to what it would have been in AB+. However it's not just a really well made mod they added and made adjustments to, there's also yet another path that's added. Dessert = +1 Flat Damage, +0.2 shot speed. Doors remain open when entering a room with enemies in it. However if you take damage a second time you die like the Lost does, Same effect as touching a white fire, but only lasts one room, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Lost, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Lilith, Spawns up to 25 random coins on the floor, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Keeper, Locusts are variants of blue flies, except they have special effects based on the color, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Apollyon, Gives you The Forgotten as a temporary familiar, with 2 Bone hearts and his bone weapon. However after the attack you end up near the boss, which puts you in danger of taking damage too, Scales in damage and area of effect with the player's size, UNLOCK: Unlock this item by defeating Delirium as Jacob & Esau, When used will do a swipe attack in any direction. princezzxdiana, pink, purple, hat, Once per room when you are damaged down to your final half a heart, you gain 1 soul heart, Re-entering a room allows this effect to be triggered again, REPENTANCE - Scapular won't grant its soul heart if the player is attempting to proc it with certain heart donation mechanics (such as IV Bag), * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, Azazel: Azazel has lots of good devil deal unlocks tied to his completion marks, like Abaddon, The Nail and Maw of the Void. pills in one run, A familiar which follows Isaac and, upon taking damage, will spawn a charmed enemy that will fight for you, When the charmed enemy is spawned the egg will crack, but regenerate in the next room, UNLOCK: Unlock this item by spawning 3 charmed enemies in a single room, Flat Stone causes your tears to bounce across the room, Whenever a tear bounces, it deals splash damage to nearby enemies for 25% of your tear damage, Added as part of the Afterbirth+ Booster Pack #5. In The Binding of Isaac: Repentance, there are two routes to unlock Jacob and Esau. Here is the requirements for getting 1001% completion rate in Binding of Isaac. Broken hearts permanently subtract from your total possible health containers, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Magdalene, Isaac turns to stone and can't move for 10 seconds, but your tear rate goes up significantly for the duration, UNLOCK: Unlock this card by defeating challenge #42 (Hot Potato), UNLOCK: Unlock this card by defeating challenge #43 (Cantripped), "May you see the value of all things in life", When used, all items and pickups in the current room are turned into money. The floor generation can fail and cause the guaranteed Planetarium to not spawn sometimes. black, white, gray, grey, guppys tail, guppy tail, Upon use, the IV Bag takes half a red heart and spawns 1-3 coins (the same effect as a blood donation machine), Can drop from a blood donation machine after playing it, In the Womb and beyond this deals 1 full heart of damage, If no red hearts exist, other types of hearts are consumed instead, With the Keeper this is changed to spawning 0-1 coins per use instead, Item Pool: None (Blood donation machine only), Places a decoy on the floor which attracts enemies and explodes after a period of time, When it explodes, it deals 185 damage to everything in radius (Same damage as Mr Mega bombs), * item room, treasure room, item room pool, worst friend, dead, baby, pink, puppet, Bombs no longer automatically explode and will only do so when you activate the remote detonator, Can be used to detonate Dr. Fetus bombs early, * boss rush pool, boss rush room, shop room pool, shop item pool, item room, treasure room, For the biggest and best experience, you'll want the Rebirth Complete Bundle on Steam, which includes the newer base game and all three expansions, clocking in at a hefty $51 when not on sale.. The spear cannot be thrown like Mom's Knife but deals damage while it is in contact with an enemy, *, grey, silver, sword, dagger, blade, knife, Tears now have a random chance to become sticky bombs, which will attach to enemies and explode after a few seconds, The bomb explosion deals your tear damage + 60, REPENTANCE - Explosivo tears now deal damage upon impact, When picked up, drops between 1-6 random pickups on the floor, Causes all item pedestals to be chosen from a random item pool instead of the pre-defined ones which normally exist, Fixed item drops won't be replaced - e.g. Rotten Meat = +1 flat damage, +1.5 range. (Does not roll your devil deal items), 5 Dot - Reroll and restart the current floor (Forget Me Now effect), 6 Dot - Reroll all of your items and all the pickups on the entire floor (Combined 1 + 3 + 4 rooms), The same order as the in-game collection page. Keeper's Sack Having trouble unlocking unlocks and achievement while having just cosmetic mods active. pill if no other pills were used yet. when entering the item room, Gives +1 Soul Heart when starting each new floor after picking this up, Currently this effect doesn't work in Greed Mode - It will show 2 items but the item rooms will have different items in them, Gives +0.4 Tears Up for each room completed without taking damage, up to a maximum of +2.0 Tears Up, When you take damage, the tears bonus is reset, Picking this item up counts and gives you a temporary +0.4 Tears Up as well, Allows you to double-tap the shoot button to create a holy shield for 1 second that pushes enemies back and deals 10 damage to them if they touch it, The shield also reflects enemy shots and beams back at them for some extra damage, Can only be activated every 3 seconds (Shown by a white glow and a ticking noise). Aries, Cancer, Capricorn, Leo etc.). Using Sumptorium as her will then cause all Clots to be consumed and return your hearts back to you. Function: Gives access to the Blue Womb no matter the time elapsed, Special interaction with Pandora's Box (consumes both for 6 random items), Unlock Condition: Defeat Isaac, ?? Time is the essence", "Sleeping gatekeepers will need to be awoken with a loud sound", UNLOCK: Unlock this card by beating Challenge #11 (Glass Cannon). This allows Isaac to potentially accrue a large number of stat upgrades. with Brimstone it fires 10 lasers), Turns your tears into bones, which shatter into 1-3 smaller bone shards upon hitting any object or enemy, The smaller bone shards deal damage equal to half your normal tear damage, UNLOCK: Unlock this item by defeating Delirium in The Void floor with Lazarus, Allows Isaac to carry two cards, runes or pills (or any combination of these) at the same time, Drops a random card, pill or rune on pickup, UNLOCK: Unlock this item by beating Greedier Mode with The Lost, Item Pool: Boss Room, Beggar, Gold/Stone Chest, *, silver, metal, grey, gray, omega, dads lost coin, dad lost coin, dad coin, REPENTANCE - This was renamed from Moldy Bread, *, sandwich, toast, brown, green, bite, bitten, Each time you take damage from any source, Cone Head has a 20% chance to prevent it from reducing your health, Isaac flashes blue very briefly when damage is negated by this item, * northernlion, nl, northern lion, ryan letourneau, egg, egg father, egg daddy, dad, BALD, northernlion's head resembles an egg much like this item, isn't that hilarious?, pink, Isaac's tears have a 20% chance to be a booger instead, which stick on to enemies and deal periodic poison damage until they die, Each tick of poison damage is equal to your normal tear damage, Each booger persists for 10 seconds or until the enemy dies. From the creative mind of Edmund McMillen came a dungeon crawler inspired by The Legend of Zelda, loaded with religious, astrological, pop culture, and toilet humor references. Enemies touching the head don't hurt Isaac, UNLOCK: Unlock this item by defeating Delirium as Tainted Forgotten, Item Pool: Boss Room, Crane Game, Golden Chest, Drops 1 random rune or soul stone when picked up, Item Pool: Shop, Golden Chest, Mom's Chest, Old Chest, Tears have a chance to become a tooth, dealing x3.2 damage, similar to Tough Love, The chance to fire a tooth with this trinket is affected by your Luck stat, At +0 luck you have ~12% chance for this effect to activate, At +9 luck every tear you fire will be a tooth, Chance to spawn half a soul heart when picking up a coin, The chance scales up based on the coin's worth: Penny = 16.66%, Double Penny = 30.5%, Nickel = 59.7%, Dime = 83.3%, UNLOCK: Unlock this trinket by defeating ??? grey, gray, Gives the player an invulnerability effect which lasts for a 10 seconds, Can be used to get free hits on the Blood Donation machines and Devil Beggars, * library pool, library room, book room pool, item room, treasure room, item room pool, white, pink, Allows Isaac to walk over gaps with a width of one tile, * shop room pool, shop item pool, the lost item pool, brown, wooden, Heals half a heart after every 13 enemies killed, Works with the Keeper for restoring coin HP, * item room, treasure room, item room pool, the lost item pool, black, grey, gray, bat, All spacebar items can now be 'overcharged', allowing them to be charged up twice instead of once, The extra charges appear in yellow on top of the normal green bars, This item works with self-recharging items, * shop room pool, shop item pool, pink, purple, 15c items are reduced to 7c. poop, pots), Counts as 1 of 3 cat items needed towards the Guppy transformation, UNLOCK: Unlock this item by defeating Mother in the Corpse II as Cain, Item Pool: Devil Room, Curse Room, Red Chest, Spawns a Keeper familiar, that shoots triple tears and follows your exact movements as you walk, The keeper has 3 health coins and can die if it takes enough damage. This includes key blocks and secret room doors, +1.0 Damage Up, but each rock tear has a random damage modifier that can go up or down (x0.5 to x2), Allows Isaac to charge by double tapping the same direction, dealing damage to any enemies caught, You are invincible while charging (doesn't include self-damage like Blood Donation machines), The dash deals x4 your current tear damage + 8, Doesn't have to be in a straight line, you can hold another button to curve it, Has a 3 second cooldown before it can be used again, While not moving your speed rapidly increases up to a bonus of +0.5, While you have this +0.5 bonus, moving will cause Isaac to fart around the room, spawning poison gas clouds, The farts stop spawning once you reach your regular movement speed, Poison deals damage equal to half your tears per tick, Isaac is immune to Poison from enemies, such as Gasbag, Gives you a wide circle halo which grants 7 orbital tears upon entering a new room, The tears orbit for 13 seconds before dropping off, Has a chance to absorb any enemy tears and add them to the orbiting tears. 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